Saliva Hormone Opendx Supreme

Test Details

Lab Company: Access Medical Labs
Sample Type: Saliva
Collection Location: At Home

The Opendx Supreme saliva test measures 11 hormones and cortisol to analyze a patient's baseline hormone levels and cortisol fluctuation throughout the day.     

🔑 Key Details 📦 Shipping
Preparation & Timing 📊 Results
🧪 Collection Instructions 📚 More Resources
💳 Requisition & Payment
💬 Questions?

Key Details 

  • If you are a menstruating female, you must collect on specific days of your cycle. 
  • If you are taking supplemental hormones, you must time your test properly after your last dosage.
  • Do not drink any caffeinated or alcoholic beverages during the collection period. 
  • Do not eat or drink for 2 hours prior to sample collection.
  • Samples should be shipped Monday - Friday only.

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Preparation & Timing

  • If you are a male or non-menstruating female, you can test any day of the month. 
  • If you are a menstruating female, collect according to the following schedule.
    • Regular periods: Collect samples on day 19, 20, or 21 of your cycle (where day 1 is the first day of your period).
    • Irregular periods: Collect samples when you are not bleeding. Collect closest to days 19, 20, and 21 of your cycle. 
  • If you are taking supplemental hormones (including melatonin, hydrocortisone, cortisol, or creams containing placental derivatives), collect according to the following schedule. 
    • Patch hormones applied daily: Collect samples 12-24 hours after applying the patch.
    • Patch hormones applied weekly or biweekly: Collect samples at the midpoint of applying patches.
    • Hormones in a gel, spray, pill, or cream: Collect samples 12-24 hours after your last dosage.
    • Hormone injections: Collect samples at the midpoint between injections. 
    • Sublingual and troche hormones: Collect samples 36 hours after your last dosage.
  • Do not drink any caffeinated or alcoholic beverages during the collection period.
  • Do not drink or eat for at least 2 hours prior to sample collection. 

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Collection Instructions

Collection Schedule

  • Collection 1: 7:00 am - 8:00 am (or as soon as you awaken)
    • Do not eat or brush your teeth prior to collection.
  • Collection 2: 11:00 am - 12:00 pm
  • Collection 3: 4:00 pm - 5:00 pm
  • Collection 4: 10:00 pm - 12:00 am (before you go to bed)
    • RED TUBE

Collection Instructions

  1. Rinse your mouth with water 15 minutes prior to collection.
  2. Wash your hands and dry them with a clean towel.
  3. Write your name, date of birth, and the collection date and time on a label.
  4. Place the label on the tube. 
  5. Collect saliva in the tube. Do not force the saliva - let it flow into the tube. 
    1. Do not get any phlegm into the tube.
    2. If you cannot produce saliva, smell food to increase saliva flow.
    3. If you make a mistake, rinse the tube with warm water ONLY, let it air dry, and collect again.
  6. Fill the tube until you have reached the maximum line. 
  7. Tightly seal the cap back onto the tube. 
  8. Place the tube into the refrigerator until you are ready to ship. 
    1. Do NOT freeze tubes.
  9. Repeat steps 1-8 for each of the four collections.
  10. Place all four tubes into the bag in which they came.
  11. Place the completed requisition form and specimen bag into the test kit box and seal. 

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Requisition & Payment

  • Your kit has been prepaid. You DO NOT need to pay anything extra.
  • A requisition form will be included in your test kit. Fill in your personal information and ship back with the samples.
    • Since you pre-paid for your tests, you do not need to fill in the payment information on any of these forms.

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  • Ship samples Monday - Friday only.
  • Ship samples using the provided materials.
    • Place the tubes into the bag in which they came.
    • Place the completed test requisition form and specimen bag into the test kit box and seal. 
    • Place the box into the provided, prepaid UPS bag and seal.
  • Drop off the samples at any UPS location.

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  • Results should be released to your provider 1-6 business days after samples are received at the lab. We cannot guarantee processing time. 
  • Your provider will notify you when your results are in and schedule a follow-up appointment for you to review them together.

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More Resources

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For general questions, email Rupa Health at For test-specific questions, contact Access Medical Labs by calling (866) 720-8386 or chatting with support