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Lab Test Instructions
Doctor's Data
NeuroAdrenal Profile - 24 hr
NeuroAdrenal Profile - 24 hr
Updated over a week ago

Test Details

Lab Company: Labrix by Doctor's Data
​ Sample Type: Urine, Saliva
​ Collection Location: At Home

The NeuroAdrenal Profile provides an assessment of HPA axis function and diurnal cortisol. These instructions are for the 24-hour urine collection.

Key Details

  • Certain foods should be avoided for 24-48 hours prior to and during collection.

  • Avoid strenuous exercise and the use of tobacco or nicotine products for 24 hours prior to and during collection.

  • Avoid supplements and medications on the day of collection, if possible.

  • You will be collecting your urine for 24 hours.

  • Samples can only be shipped Monday - Friday.

  • The samples and the provided ice pack should be frozen for at least 4-6 hours prior to shipping.

    • Keep them in the freezer until you ship.

Preparation & Timing

  • If you are a menstruating woman, collect one day during days 19-23 of your menstrual cycle (assuming a 28-day cycle).

    • Day 1 of your cycle is the first day of your period.

  • If you are taking topical hormones,

    • Your last dose prior to collection should be 12-24 hours before collecting your first sample.

    • Do NOT use them during the day of saliva collection.

  • If you are taking sublingual hormones or troches,

    • Your last dose prior to collection should be 24-36 hours before collecting your first sample.

    • Drink 2 full glasses of water after taking your last dose to clean the tissues.

    • Do NOT take them during the day of saliva collection.

  • If you are taking hormone injections, subcutaneous pellets, or transdermal patches,

    • Collect your samples at the halfway point between doses.

  • If you are taking oral hormones (pills) or transdermal patches,

    • Use as prescribed on the day of collection.

  • If you are taking a cortisol supplement, glucocorticoid, or cortisol-containing medication, consult your healthcare provider prior to collecting your samples.

    • It is recommended to stop using these products 5 days prior to sample collection.

    • Consult with your healthcare provider prior to discontinuing any prescription medications.

  • Avoid the following foods for 2 days before and during collection:

    • Avocados

    • Eggplant

    • Tomatoes

    • Bananas

    • Melons

    • Pineapple

    • Grapefruit

    • Plums

    • Nuts

    • Nut butter

    • Wine

    • Cheese

    • Rice

    • Chocolate

  • Avoid the following foods, products, and activities for 24 hours prior to and during collection:

    • Alcohol

    • Coffee

    • Tea

    • Caffeinated beverages

    • Strenuous exercise

    • Tobacco products

    • Nicotine products

    • Anti-aging creams

  • Avoid all supplements and medications on the day of collection.

    • Consult with your healthcare practitioner prior to discontinuing any prescription medications.

  • You will be collecting your urine for 24 hours.

  • For your saliva collection,

    • Do not drink or eat anything for 1 hour prior to collection.

    • Do not brush or floss your teeth or have dental work done for 30 minutes prior to collection.

Collection Instructions

Saliva Collection

  1. Collection Schedule - You MUST follow this schedule.

    1. Collection 1: 30 minutes after waking (pink tube)

    2. Collection 2: noon/before lunch (green tube)

    3. Collection 3: evening/before dinner (orange tube)

    4. Collection 4: night/right before bed (blue tube)

  2. Wash your hands.

  3. Rinse your mouth with water.

  4. Wait 10 minutes before beginning collection.

  5. Collect your saliva into the appropriate tube (see schedule above).

    1. Fill the tube 3/4 full (bubbles are okay).

    2. You can use the included straws to help funnel saliva into the tube.

  6. If you have trouble producing saliva, try

    1. Yawning

    2. Thinking of your favorite food

    3. Touching your tongue to the roof of your mouth.

  7. When the tube is 3/4 full, snap the tube closed tightly.

  8. Write the date and time of collection on the tube and requisition form.

  9. Place the saliva tube in the freezer immediately.

  10. Repeat steps 2-9 for each of the four collections.

  11. When all four tubes have been collected, place them in the plastic bag with the absorbent material.

  12. Keep all saliva tubes in the freezer until you are ready to ship them.

Urine Collection

  1. When you wake up, urinate and do not collect.

  2. You will collect your urine for 24 hours.

    1. The collection period will start with your second urination on day 1.

    2. The collection period will end with your first urination on day 2.

  3. For each urination, collect urine in the collection cup.

  4. Pour the urine into the large orange collection container.

  5. Place the collection container in the refrigerator.

  6. Once all of the urine has been collected, place the orange collection container on a level surface.

  7. Read the volume from the markings on the container.

  8. On the requisition form, note the total volume you collected.

  9. Shake the large container to mix the urine.

  10. Pour the urine into the specimen vial.

    1. Do NOT touch or discard the preservative in the vial.

  11. Fill the vial to the FILL LINE.

    1. Do NOT underfill.

  12. Close the vial tightly.

  13. Gently shake the tube to mix the urine with the preservative.

  14. Place the vial in the plastic ziplock bag with the absorbent material.

  15. Seal the bag.

  16. Freeze the urine sample and the provided ice pack for at least 4-6 hours.

    1. Keep the sample in the freezer until you are ready to ship.

Requisition & Payment

  • Your kit has been prepaid. You DO NOT need to pay anything extra.

  • Instructions on how to fill out your requisition can be found HERE.

    • Since you pre-paid for your tests, you do not need to fill in the payment information on any of these forms.

    • Make sure to note the total volume collected on the requisition form.

Shipping

  • Ship Monday - Friday only.

  • Freeze the ice pack for at least 4-6 hours prior to shipping.

  • To prepare your samples for shipping,

    • Remove the urine sample and saliva samples from the freezer.

    • Place the insulated cooler into the cardboard test kit box.

    • Place the urine sample in the insulated cooler.

    • Place the saliva samples in the insulated cooler.

    • Place the frozen ice pack into the insulated cooler.

    • Place the completed test requisition form into the insulated cooler.

    • Place the lid on the cooler and close the cardboard box.

    • Place the cardboard box into the FedEx Clinical Pak.

    • Fill in your information on the Billable Stamp and place it on the FedEx Clinical Pak.

      • Keep the customer receipt.

  • Make a note of your tracking number so that you can track the sample back to the lab.

  • Ship using FedEx.

    • Do NOT place your samples in a FedEx drop box.

    • You can schedule a FedEx pickup by calling 1-800-463-3339.

      • At the automated greeting, say, "schedule a pickup."

      • At the next prompt, say, "schedule a pickup with a label or stamp."

      • You will be asked if the waybill says "stamp" - say, "yes."

      • Then give your address information.

Results

  • Results should be released to your provider 5-7 business days after samples are received at the lab. We cannot guarantee processing time.

  • Your provider will notify you when your results are in and schedule a follow-up appointment for you to review them together.

More Resources

Questions?

For general questions, email Rupa Health at support@rupahealth.com. For test-specific questions, contact Doctor's Data by calling 800-323-2784 or chatting with support.

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