DUTCH Sex Hormone Metabolites



Test Details

Test Company: Precision Analytical
Test Type:
Collection Location:
 At Home

The DUTCH Sex Hormone Metabolites is the ultimate test for HRT monitoring and great for baseline measurements as well. It is a unique method for more accurate vaginal hormone and oral progesterone monitoring. This test is run on GC-MS/MS: More accurate than LC-MS/MS or GC-MS for sex hormone metabolites!

These results include:

  • Extensive Estrogen Metabolites: E1, E2, E3, 2-OH-E1, 4-OH-E1, 16-OH-E1, 2-Methoxy-E1, 2-Methoxy-E2, 2-OH-E2, 4-OH-E2.
  • Extensive Androgen Metabolites: Testosterone, DHEAs, DHT, and more (7)
  • Progesterone Metabolites: b-Pregnanediol, a-Pregnanediol (2)
  • Graphical representation of results and embedded video tutorials to assist in the hormone assessment to share with your medical provider

Planning & Timing

  • Make sure to avoid the following for 72 hours prior to collection:

    • Avocados, bananas, pineapple, pineapple juice, plantains, plums, eggplant, kiwi, butternuts, pecans, and walnuts
  • Men & non-cycling women: can take any day
  • Women with a cycle: Need to coordinate timing with menstrual cycle. If irregular cycle - watch this video
  • If you have an irregular cycle or are not sure if you are still cycling: purchase an ovulation predictor kit from you local drugstore. Take this test everyday until you see the first FAINT sign of ovulation. Count 5-7 days from this first faint positive and that is your collection window.
  • If you have a regular cycle: Use this table to determine when you should collect your sample:
    Length of your cycle (days)
    Collect during these days of your cycle
    20 11-13
    21 12-14
    22 13-15
    23 14-16
    24 15-17
    25 16-18
    26 17-19
    27 18-20
    28 19-21
    29 20-22
    30 21-23
    31 22-24
    32 23-25
    33 24-26

Collection Instructions 

  • Your kit will come with detailed instructions
  • Here is a video on how to collect your sample


  • Your provider will notify you when results are in and schedule a follow-up to review them together

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