Test Details
Lab Company: Genova Diagnostics
Sample Type: Buccal Swab
Collection Location: At Home
The Genomic SNP Sex Hormone add-ons (MTHFR, COMT, VDR, and CYP1B1) evaluate genetic variations.
Key Details
You will collect your samples on the same day as your urine collection.
Certain medications may affect test results (see list below).
You must collect on specific days of your cycle.
You must decrease your fluid intake 24 hours prior to collection.
You must avoid certain activities the night prior to and the day of collection.
Samples should be collected upon waking.
Ship your sample within 48 hours of collection.
Rupa Health recommends shipping Monday - Thursday only to avoid shipment delays.
Preparation & Timing
You will collect your samples on the same day as your urine collection.
You must collect on specific days of your cycle.
Premenopausal women: Collect between Day 19 and Day 25 of your cycle.
Day 1 is the first day of your period.
Menopausal women: Collect on any day.
If this is a follow-up test, you must collect your sample on the same day of your cycle, or the same phase of hormone therapy, as you did previously.
If you take hormone replacement therapy or oral contraceptives, continue dosing as usual.
Avoid the following foods for 48 hours prior to sample collection.
Flax seeds (whole or ground)
Sesame seeds (whole or ground)
Limit your fluid intake 24 hours prior to sample collection.
Drink no more than 0.5 oz fluid/pound of body weight.
Example: A 130-lb person should drink no more than 65 oz of fluids.
The night before sample collection
Brush your teeth as normal
Floss your teeth as normal
Do NOT use mouthwash
Avoid the following activities on the day of sample collection.
Eating
Drinking anything but water
Brushing your teeth
Flossing your teeth
Samples should be collected upon waking.
Collection Instructions
Collect your samples immediately upon waking (before eating, drinking, brushing your teeth, etc.).
Thoroughly wash your hands with soap and warm water.
Dry your hands with a clean towel.
Gently peel open the package labeled "Sterile Cotton Tipped Applicator."
Keep the package intact.
Only peel it open enough to remove the applicator.
Remove ONE cotton swab applicator.
DO NOT touch the cotton tip.
Open your mouth widely.
Insert the cotton tip of the swab applicator.
Aggressively scrape the inside of your cheek for at least 30 seconds.
Use a back and forth, up and down motion.
Rotate the applicator several times.
Swab between the cheek and gums.
Avoid excessive saliva.
Allow the swab to air dry for 15-20 minutes.
DO NOT let the cotton tip touch any surface or your hands.
Repeat steps 5-9 with the second swab.
Complete the test registration (instructions HERE).
Please ensure that the name on the registration matches the name on your Rupa order EXACTLY. If it does not match, you may need to recollect your samples.
Once the swabs have dried, place them back into the applicator package, cotton tip first.
Write the following information on the label and place it on the envelope.
Patient's full name - Please ensure that the name on the label matches the name on your Rupa order EXACTLY. If it does not match, you may need to recollect your samples.
Date of collection
Insert the swab applicator package into the provided envelope and seal.
Requisition & Payment
Your kit has been prepaid. You DO NOT need to pay anything extra.
Instructions on how to complete your test registration can be found HERE.
Since you pre-paid for your tests, you do not need to fill in the payment information on this form.
Shipping
Ship your samples within 48 hours of collection.
Rupa Health recommends shipping Monday - Thursday only to avoid shipment delays.
To prepare your samples for shipping,
Place the swab applicator package into the letter envelope.
Seal the envelope.
Place the envelope into the test kit box.
Place the urine sample into the test kit box.
Place the completed activation card into the test kit box.
Place the test kit box into the provided return mailer.
Seal the return mailer.
Make a note of the tracking number so that you can track your sample back to the lab.
Ship your samples via FedEx.
You can take your samples to the nearest FedEx location.
DO NOT place your samples in a drop box.
You can also schedule a FedEx pickup by calling 1-800-463-3339 or visiting their website www.fedex.com.
Results
Results should be released to your provider 7-21 business days after samples are received at the lab. We cannot guarantee processing time.
Your provider will notify you when your results are in and schedule a follow-up appointment for you to review them together.
More Resources
Test Information Pages
Collection Instructions
Other Information
Questions?
For general questions, email Rupa Health at support@rupahealth.com. For test-specific questions, contact Genova Diagnostics by calling 800-522-4762 or chatting with support.