Test Details

Lab Company: The Great Plains Laboratory
Sample Type: Urine
Collection Location: At Home

This is a single-marker test measuring kryptopyrrole. High levels of circulating kryptopyrrole can quickly deplete zinc and vitamin B6. 

🔑 Key Details 📦 Shipping
Preparation & Timing 📊 Results
🧪 Collection Instructions 📚 More Resources
💳 Requisition & Payment
💬 Questions?

Key Details 

  • Do not collect samples while menstruating.
  • Limit liquid intake the night prior to collection. 
  • You will collect your sample upon waking.
  • Freeze your sample before shipping.
  • Samples may only be shipped Monday through Thursday.
  • DO NOT fill out any information on

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Preparation & Timing

  • Save the cardboard box - you will use this to ship back your sample.
  • DO NOT collect samples while menstruating.
  • The night prior to collection 
    • Limit liquid intake starting at 6 pm.
  • The day of collection 
    • You will collect your sample upon waking.
    • DO NOT eat or drink prior to collecting your sample.

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Collection Instructions

  1. Collect your first morning urine in the provided collection cup. 
    1. Collect prior to eating or drinking. 
  2. Pour urine into the amber vial labeled "Kryptopyrrole."
    1. DO NOT touch or discard the preservative in the tube.
  3. Screw the top on the vial tightly.
  4. Invert the vial 10 times.
  5. Place the amber vial and the provided gel pack into the freezer.
    1. The sample and gel pack should remain in the freezer for a minimum of 4 hours prior to shipping.
    2. Keep them in the freezer until ready to ship.
  6. Place the amber vial into the biohazard zip-lock bag along with the absorbent sheet.
  7. Place the frozen gel pack and the sample into the silver thermo bag.
  8. Place the silver thermo bag into the cardboard box.
    1. If the sample is not in the box, it will be rejected by FedEx.
  9. Place the completed test requisition form into the box and close the lid.

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Requisition & Payment

  • Your kit has been prepaid. You DO NOT need to pay anything extra.
  • Instructions on how to fill out your requisition can be found HERE.
    • Since you pre-paid for your tests, you do not need to fill in the payment information on any of these forms.
    • DO NOT fill out any information on

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  • Sample must be frozen for a minimum of 4 hours prior to shipping.
  • To prepare your sample for shipping,    
    • Place the amber vial into the biohazard zip-lock bag. 
      • Ensure the absorbent sheet is in the bag as well. 
    • Place the frozen gel pack and the sample into the silver thermo bag.
    • Place the silver thermo bag into the cardboard box. 
    • Place the completed test requisition form into the box.
    • Seal the cardboard box. 
    • Place the cardboard box into the provided FedEx Clinical Pak Mailer.
  • Ship via FedEx, Monday - Thursday only.
    • You can take your sample to the nearest FedEx location.
    • Do NOT put your sample in a FedEx drop box.
    • You can also schedule a FedEx pickup by calling 1-800-463-3339
      • When the automated greeting begins, say, “Schedule a pickup.”
      • When asked if your label has the word “Stamp” on it, say, “Yes.”
      • Let them know you are shipping using a Billable Stamp.
      • Your tracking number can be found on the Return Label.
  • Make a note of your tracking number (found on the Return Label) so that you can track your sample back to the lab.

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  • Results should be released to your provider 7-21 business days after samples are received at the lab. We cannot guarantee processing time. 
  • Your provider will notify you when your results are in and schedule a follow-up appointment for you to review them together. 
  • Your provider may choose to release your results to you. Rupa cannot release your results without provider authorization.

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More Resources

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For general questions, email Rupa Health at For test-specific questions, contact The Great Plains Laboratory by calling 1-800-288-0383 or chatting with support