Test Details

Lab Company: Genova Diagnostics
Sample Type: Saliva
Collection Location: At Home

The Male Hormones Plus™ measures testosterone, cortisol, DHEA, and melatonin to analyze a patient's hormone levels and imbalances.

Key Details

All samples (including add-ons) must be collected on the same day.
Consider waking at 6 am on the day of your collection.
If you have recently taken or are taking certain medications (see list below), consult your healthcare provider prior to testing.
If you have the Cortisol Awakening Response (CAR) add-on, you will collect two additional samples.
Rupa Health recommends shipping your samples Monday - Thursday only to avoid shipment delays

All samples must be collected on the same day.
- Consider waking at 6 am on the day of your collection.
If you have taken any of the following medications in the last 12 months, consult your healthcare provider before taking this test.
- Transdermal (cream) hormones
- Sublingual hormones
If you have taken any of the following drugs, herbs, or supplements in the last 3 months, consult your healthcare provider prior to taking this test.
- Ketoconazole
- Cimetidine (Tagamet)
- Anastrozole (Arimidex)
- Letrozole (Femara)
- Exemestane (Aromasin)
- Chrysin
- Apigenin
- Tribulus terrestris
- Clomiphene
- Antiepileptics
- Digoxin
- Oral steroids (e.g. Prednisone)
- Cortisone cream
- Any steroid-based nasal sprays, inhalers, or eye drops
The night before collection, set out the supplies for your first morning collection.
- Collection tube
- Glass of water
- Low-level light
  - DO NOT turn on a bright light when you first wake up.
Avoid the following activities for 1 hour prior to each collection:
- Eating
- Drinking anything except water
- Brushing your teeth
- Flossing your teeth
- Using mouthwash
- Chewing gum
- Using tobacco products

The night before collection, place the following items by your bed.
1. Collection tube
2. Glass of water
3. Low-level light
Upon waking, DO NOT turn on a bright light until you have completed the 7:00 am - 9:00 am collection.
Fill the collection tube with saliva until you reach the 3-ml mark.
1. You should finish the collection within 5 minutes of starting.
2. Your sample should not contain bubbles or mucus.
Replace the cap tightly.
Write the following information on the appropriate label (ie: label 1 for collection 1). Attach the label to the collection tube.
1. Your first and last name
2. Time of collection
3. Date of collection
Place the tube into the biohazard bag.
Freeze the tube (in the bag) immediately.
1. Samples should be frozen a minimum of 2 hours prior to shipping.
2. Keep samples frozen until ready to ship.
Repeat steps 3-7 for each collection (schedule HERE).
Complete the test registration (instructions HERE).
1. Please ensure that the name on the registration matches the name on your Rupa order EXACTLY. If it does not match, you may need to recollect your samples.
When you are ready to ship the samples, place the frozen samples in the biohazard bag.
Place the biohazard bag into the test kit box.
Place the test kit box and completed activation card into the provided, prepaid mailing envelope.

Your kit has been prepaid. You DO NOT need to pay anything extra.
Instructions on how to complete your test registration can be found HERE.
- Since you pre-paid for your tests, you do not need to fill in the payment information on this form.

Ship your samples as soon as possible after collection.
Rupa Health recommends shipping Monday - Thursday only to avoid shipment delays
To prepare your samples for shipping,
- Place the frozen sample tubes into the biohazard bag.
- Place the biohazard bag into the test kit box.
- Place the test kit box into the provided return mailer.
- Place the completed activation card into the provided return mailer.
Make a note of the tracking number on the label so that you can track your samples back to the lab.
Ship your samples via FedEx.
- You can take your samples to the nearest FedEx location.
- DO NOT place your samples in a drop box.
- You can also schedule a FedEx pickup by calling 1-800-463-3339 or visiting their website www.fedex.com.

Results should be released to your provider 7-21 business days after samples are received at the lab. We cannot guarantee processing time.
Your provider will notify you when your results are in and schedule a follow-up appointment for you to review them together.

For general questions, email Rupa Health at [email protected]. For test-specific questions, contact Genova Diagnostics by calling 800-522-4762 or chatting with support.